The N3C Data Enclave is a secure platform through which harmonized clinical data provided by our contributing members are stored. The Enclave includes demographic and clinical characteristics of patients who have been tested for or diagnosed with COVID-19, and further information about the strategies and outcomes of treatments for those suspected or confirmed to have the virus. Additional data from individuals infected with pathogens such as SARS 1, MERS, and H1N1 are also included to support comparative studies. Data can be accessed only within the N3C Data Enclave and cannot be downloaded or removed. Three tiers of access are available for users depending on the scope and nature of their research; however, all will require verification and approval by the Data Access Committee (DAC) before data can be accessed.