The dataset "Laboratory-confirmed influenza cases in Germany" provides weekly influenza case counts and incidence rates of influenza cases confirmed by laboratory testing, reported by health authorities to the Robert Koch Institute (RKI) under the German Infection Protection Act. It includes only cases with direct laboratory evidence of influenza infection, excluding clinically or epidemiologically confirmed cases, and is updated weekly to support standardized surveillance, early detection, and public health response to influenza outbreaks across Germany.